Acyclovir Suppression to Prevent Recurrent Genital Herpes at Delivery
نویسندگان
چکیده
منابع مشابه
Acyclovir suppression to prevent recurrent genital herpes at delivery.
OBJECTIVE To determine if suppressive acyclovir near term decreased the frequency of clinical recurrences at delivery in women with recurrent genital herpes simplex virus (HSV) infection. METHODS We conducted a prospective, double-blind, randomized trial in 234 women with recurrent genital herpes. Women with genital infection of any frequency were enrolled. Patients received either suppressiv...
متن کاملAcyclovir Suppression to Prevent Clinical Recurrences at Delivery After First Episode Genital Herpes in Pregnancy: An Open-Label Trial
OBJECTIVE To continue evaluation of the use of acyclovir suppression in late pregnancy after first episode genital herpes simplex virus (HSV) infection, using an open-label study design. METHODS Ninety-six women diagnosed with genital herpes for the first time in the index pregnancy were prescribed suppressive acyclovir 400 mg orally three times daily from 36 weeks until delivery in an open-l...
متن کاملSuppression of frequently recurring genital herpes: acyclovir v inosine pranobex.
The suppressive action of acyclovir and inosine pranobex was compared in a randomised double blind controlled trial in patients with frequently recurring genital herpes. Fourteen patients received acyclovir and 17 inosine pranobex. Treatment continued for 12 weeks. The time to the first recurrence was significantly longer and the frequency of recurrences significantly less in the recipients of ...
متن کاملAcyclovir vs isoprinosine (immunovir) for suppression of recurrent genital herpes simplex infection.
OBJECTIVE To compare the efficacy and safety of oral acyclovir (400 mg twice daily) with oral isoprinosine (500 mg twice daily) in the suppression of recurrent genital herpes. DESIGN Double-blind, double-dummy, randomised, controlled, parallel group trial. SETTING 13 centres in UK, Belgium and Germany. SUBJECTS 127 immunocompetent patients with frequently recurring genital herpes. MAIN ...
متن کاملAcyclovir prophylaxis to prevent herpes simplex virus recurrence at delivery: a systematic review.
OBJECTIVE Genital herpes simplex virus (HSV) infection is one of the most common viral sexually transmitted diseases in the United States. Perinatal transmission of the virus to the fetus or neonate is a major concern in affected pregnancies. Our objective was to systematically review published data to estimate the effect of prophylactic acyclovir provided to pregnant women near term on the rat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Infectious Diseases in Obstetrics and Gynecology
سال: 2002
ISSN: 1064-7449,1098-0997
DOI: 10.1155/s1064744902000054